So what are fluorophores? To make it easier to understand fluorophores are a chemical compound which produces a reaction when in contact with light. An example you may consider is you know when you are watching those crime movies and the lab technician checks for blood stains with a glowy stick? Exactly! Those are fluorophores.
Fluorophores were discovered by Nicolas Monardes, a Spanish physician and botanist in 1565. He described finding a bluish fluid from the wood of a small Mexican tree.